New study shows SARS-CoV-2, the strain of coronavirus that causes COVID-19, can infect human adipose tissue .
Many people of all ages and health conditions have been infected with COVID-19 since the beginning of the pandemic. Although it affects people differently, there are a number of known factors that increase the risk of a more difficult recovery. These include being overweight, which is a risk factor for many health problems.
“Overweight or obesity also contributed to 'poor COVID-19 outcomes' for patients, such as requiring a ventilator to breathe more often. Scientists have found that there may be a more direct reason for how Covid affects people who are overweight. SARS-CoV- 2 can infect human adipose tissue. The study involved infecting adipose tissue taken from 22 patients who had undergone surgery with a strain in the laboratory. A specific strain of coronavirus can directly infect adipose tissue, “says physician Irina Andreeva specifically for MedicForum.
This launches virus replication cycle in adipocytes (resident fat cells) and leads to inflammation of immune cells located in adipose tissue. In turn, previously uninfected cells in the tissue can also become inflamed.
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Adipose tissue susceptibility to SARS-CoV-2 infection may play a role role in making obesity a risk factor for COVID-19.
Infected adipose tissue releases exactly the same inflammatory chemicals you see in the blood of severe Covid patients. It is reasonable to assume that the presence of a large amount of infected fat may contribute to the overall inflammatory profile of critically ill patients with COVID-19.
Our heart and kidneys, surrounded by adipose tissue, can be adversely affected by tissue inflammation.
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