Scientists from Australia have shown that vitamin D deficiency increases the risk of mortality. At the same time, even a slight increase in the level of this vitamin reduces the risk of death.
Through the Mendeleian randomization approach, which uses genetic variants as proxy indicators for external factors affecting vitamin D levels, scientists have shown that deficiency of this nutrient increases the risk of mortality. Factors that affect vitamin levels, such as sun exposure or food intake, were also taken into account. The study was able to analyze the relationship between vitamin deficiency and the impact on human health, including mortality, which cannot be achieved in randomized clinical trials for well-understood ethical reasons.
Vitamin D levels less than 10 nmol increase the risk of death
There is a proven link between genetically predictable vitamin D levels and mortality from several major causes. A causal relationship has been established, which is of great importance. Unlike other types of observational studies, some methodological hurdles have been overcome.
Vitamin D deficiency triples the risk of premature death
Data from this study show the importance of the blood vitamin D threshold of 50 nanomoles per liter. They are consistent with previous observations that showed that the benefits of vitamin D supplementation were mainly seen in people with vitamin D deficiency. (READ MORE)
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