Researchers from the Netherlands in the course of studying the brain of almost 25,000 people came to an interesting conclusion. The shape of the brain in steroid users and non-users was different.
Patients with asthma, arthritis, and eczema are regularly prescribed steroid-based medications. Their side effects are well known and typically include anxiety, mood swings and depression. However, scientists from the University of Leiden in the Netherlands found that these drugs could possibly change the structure of the brain, which confirmed scans of this organ in almost 25,000 people. Patients who took glucocorticoids had less white matter, the tissue that connects brain regions.
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The Dutch scientists believe their discovery could explain the association of these drugs with neurological problems. Although this has never been scientifically proven, there is a widespread belief that some of the crippling neurological symptoms are caused by steroids. The new research has not proven the drug's definitive fault, but has identified a potential mechanism.
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Probably glucocorticoids cause changes in the brain, but more research is needed to confirm these results. Glucocorticoids are a class of steroids that are used to treat asthma, arthritis, and eczema. They are effective in reducing inflammation and suppressing the immune system, but are associated with serious side effects such as hypertension, diabetes, and weakened bones. (READ MORE) 
Leiden University
Medicine
Leiden University