Scientists from the University of Louisiana have developed an experimental human cell line from retinal pigment epithelium cells. They are necessary to study degenerative diseases of this part of the eye.
The retinal pigment epithelium cells are part of the blood-retinal barrier and protect the integrity of the photoreceptors important for vision. However, these cells are at constant risk of oxidative stress due to being in an oxygen rich environment and facing a high flux of polyunsaturated fatty acids and increased metabolic activity. Violation of the protection of these cells leads to degenerative diseases of the retina, including the very common age-related macular degeneration.
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The new cells made it possible to study events related to biology, which is involved in the normal process of repairing cellular structures damaged by oxidative stress. The created new cell line facilitates the search for the mechanisms of aging gene programming and reveals the relationship between these mechanisms in the normal cell cycle for neuroprotection and during its survival.
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Age-related macular degeneration is the most common cause of blindness in developed countries, especially in people over 60 years of age. It accounts for 8.7% of all cases of vision loss in the world. And that is why developments in the field of creating a new cell line are valuable. (READ MORE) 
University of Louisiana
Medicine
Public research university in Baton Rouge, Louisiana, USA. The premier institution of the Louisiana State University System.