Scientists from the University of Sydney have found that heredity affects the risk of developing aggressive prostate cancer. These data were obtained by genetic sequencing of tumors.
Material for this sequencing was taken from donors in Australia, Brazil and South Africa. Scientists have identified a new prostate cancer taxonomy or classification scheme and the factors that trigger it. She not only distinguishes patients by their genetics, but also predicts which tumors can become life-threatening and which are threatening, that is, in need of immediate removal. Note that in many cases, prostate cancer does not require treatment at all, it can, without causing any harm, exist in the human body until old age. And in some other cases, it must be removed immediately, since it aggressively develops and metastasizes.
Aggressive ram in France killed 94-year-old pensioner
The researchers emphasize that the current understanding of prostate tumors has been severely limited by the fact that studies have been conducted in Western populations. And belonging to an African ethnic group more than doubles the risk of deadly prostate tumors. So heredity is the key to unraveling the co-influence of genetic and non-genetic risk factors And in the African region, prostate tumors are “silent killers.”
Aggressive prostate cancer linked to 5 bacteria
Through sophisticated whole genome sequencing, more than 200,000 tumor-specific genomic variants have been identified in 183 untreated prostate tumors in men from three regions of the world. It turned out that Africans are affected by a large number of both spectrum-acquired and genetic changes, which provoke significant consequences, taking into account their heredity in the control and treatment of prostate tumors. (READ MORE) 
University of Sydney
Medicine
The oldest public university in Australia. It was founded on 1 October 1850 in accordance with the University of Sydney Act